Symbol
Name
ID

Ltbr
lymphotoxin B receptor
MGI:104875

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Mouse Phenotypes

abnormal thymus epithelium morphology

abnormal thymus medulla morphology

small thymus medulla

enlarged spleen

decreased neutrophil cell number

absent marginal zone B cells

increased B-1 B cell number

increased B cell number

decreased NK cell number

decreased CD4-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

increased NK T cell number

decreased alpha-beta T cell number

decreased single-positive T cell number

increased T cell number

increased lymphocyte cell number

abnormal lymphocyte morphology

abnormal gamma-delta T cell morphology

abnormal spleen morphology

abnormal spleen B cell follicle morphology

absent spleen germinal center

abnormal spleen periarteriolar lymphoid sheath morphology

decreased spleen white pulp amount

abnormal B cell physiology

decreased IgE level

abnormal IgG level

impaired natural killer cell mediated cytotoxicity

abnormal macrophage physiology

Availability

Mouse Genotype

Ltbr^m1Btlr/Ltbr^m1Btlr

Ltbr^m2Btlr/Ltbr^m2Btlr

Ltbr^m3Btlr/Ltbr^m3Btlr

Ltbr^m4Btlr/Ltbr^m4Btlr

Ltbr^tm1Kpf/Ltbr^tm1Kpf

Ltbr^tm1Mmat/Ltbr^tm1Mmat

Ltbr^tm1.1Thhe/Ltbr^tm1.1Thhe
Lyz2^tm1(cre)Ifo/Lyz2⁺ (conditional)

Ltbr^tm1Avt/Ltbr^tm1Avt
Tg(Vil1-cre)997Gum/0 (conditional)

Ltbr^tm1Avt/Ltbr^tm1Avt
Tg(Rorc-cre)1Litt/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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